Programme
Monday 17 March 2025, Day 0 of the Workshop:
Reception Social: Join us for a welcoming reception in the scenic grounds of Bushy House, an 18th-century historic building located on the NPL site. The evening will feature British-inspired cocktails and lawn games, such as croquet, weather permitting. We will be providing food, through a local artisanal pizza company, and running a "pub quiz".
Tuesday 18 March 2025, Day 1 of the Workshop:
08.30 - 09.00: Registration and Coffee
09.00 - 09.15: Welcome Talks, Sam Flynn and Russell Thomas, United Kingdom
09.15 - 10:00: State of Minibeam Radiotherapy, Yolanda Prezado, France
10:00 - 10:15: Challenges combining proton minibeams with target motion, Oxana Actis, Switzerland
10:15 - 10.30: Generation of micrometer electron beam from FLASHlab@PITZ, Xiangkun Li, Germany
10:45 - 11:00: MiniBee Project: Proton minibeam beamline for preclinical experiments in small animals, Aikaterini Rousseti, Germany
11:00 - 11:15: Coffee Break
11:15 - 11:35: Exploring Technical and Clinical Aspects of Lattice Radiotherapy, Maxwell Robinson/Adam Aitkenhead, United Kingdom
11:35 - 11:50: A Preclinical Setup to Inform the Clinical Introduction of Lattice Radiotherapy, Kristoffer Petersson, United Kingdom
11.50 - 12:05: Design and Characterization of Electron Minibeams from a Modified Clinical Accelerator, Umberto Deut, Italy
12:00 - 12:30: How can BeO optically stimulated luminescence dosimeters (OSLDs) be optimized for precise dose measurements in particle minibeam therapy (PMBT)? Gedchadapars Rattanasupha, France
12:30 - 13:30: Lunch
13:30 - 14:15: Limitations of TRS-398 and existing codes of practice, Hugo Palmans, United Kingdom
14:15 - 14:30: Exploiting the lateral fluence ripple from 3D-range modulators for proton mini-beam radiotherapy, Daria Boscolo, Italy
14:30 - 14:45: Designing a Compact Spatially Fractionated Range Shifter for Proton Radiobiology, Rebecca Habgood, United Kingdom
14:45 - 15:00: Adapting a radiopharmaceutical production medical cyclotron for high LET proton radiobiology studies at conventional and ultra-high dose rates with minibeam capabilities, Eva Kasanda, Switzerland
15:00 - 15:30: Are Radiochromic Films Suitable for Absorbed Dose in PMBT?, Mohammed Hussain, United Kingdom
15:30 - 15:45: Coffee Break
15:45 - 16:15: Clinical Perspective of PMBT, Emmanuel Jouglar, France
16:15 - 16:30: Status of the INFN MIRO (MInibeam RadiOtherapy) project and first biological investigations of the minibeam effect with electron beams, Francesco Romano, Italy
16:30 - 16:45: Enhanced peak-to-valley dose ratio for mega-voltage photon mini-beam radiotherapy using magnetically confined electrons, Annalisa Walpen, Switzerland
16:45 - 17:00: Interlacing Proton, Helium, and Carbon Ion Minibeams in Longitudinally Heterogeneous Treatment Plan Simulations, Thandar Aung, Germany
17:00 - 17:15: Design and Characterization of Electron Minibeams from a Modified Clinical Accelerator, Umberto Deut, Italy
19:00: Meal reservation at The King's Head, Teddington
Wednesday 19 March 2025, Day 2 of the Workshop:
09:00 - 09:30: Unanswered Questions in Radiobiology, Jason Parsons, United Kingdom
09:30 - 09:45: Experimental Evidence and Quantification of pMBRT’s Efficacy in Normal Tissue Sparing in a Murine Model, Fardous Reaz, Denmark
09:45 - 10:00: Proteomic Investigation of Rat Orthotopic Glioblastoma and Healthy Brain Responses to Proton Minibeam Radiation Therapy, Loris Roncali, Spain
10:00 - 10:15: Neon Minibeam Radiotherapy: Tissue Preservation in Abdominal Irradiation, Angela Corvino, France
10:30 - 11:00: Exploring the Role of Tissue Organization in Proton Minibeam Radiotherapy, Judith Reindl, Germany
11:00 - 11:15: Coffee Break
11:15 - 11:30: Study of the biomolecular response to neon minibeam radiation therapy in healthy and tumour cell lines through synchrotron-based infrared microspectroscopy, Roberto González Vegas, Spain
11:30 - 11:45: Use of a CMOS detector in the commissioning of a proton/helium ion microbeam facility, Tony Price, United Kingdom
12:00 - 12:15: Advancing pMBRT for Clinical Use: Experimental Validation of Proton Minibeam Dose Calculations Using a Commercial TPS Platform, Jessica Neubauer, Germany
12:30 - 13:30: Lunch
13:30 - 14:00: Clinical implementation of novel particle therapies: Proton Pencil Beam Scanning and Ultra-high dose rate proton FLASH, Richard Amos, United Kingdom
14:00 - 15:30: Roadmap for Clinical Transition Breakout Groups
15:30 - 15:45: Coffee Break
15:45 - 16:45: Roadmap for Clinical Transition Discussion
16:45 - 17:00: Goodbye, and Invitation to the 4th PMBT Workshop
Note: The timing of this programme may be subject to change at short notice.
Sister Workshop: Proton Physics Research and Implementation Group (PPRIG)
NPL will also be hosting the 7th Proton Physics Research and Implementation Group (PPRIG) Workshop on the 20 and 21 of March 2025, immediately following the PMBT workshop. Established in 2012, PPRIG brings together researchers and industry professionals to collaborate on proton therapy research and its clinical applications. The two-day PPRIG event includes:
Invited speakers
Conference talks
Poster sessions
Discussions on emerging proton therapy techniques and innovations
Participants of the PMBT workshop are welcome to extend their stay and join the PPRIG workshop for a deeper dive into proton therapy research and standards. More up to date information will be available at http://www.pprig.co.uk/pprig/meetings/.
Reception Social: Join us for a welcoming reception in the scenic grounds of Bushy House, an 18th-century historic building located on the NPL site. The evening will feature British-inspired cocktails and lawn games, such as croquet, weather permitting. We will be providing food, through a local artisanal pizza company, and running a "pub quiz".
Tuesday 18 March 2025, Day 1 of the Workshop:
08.30 - 09.00: Registration and Coffee
09.00 - 09.15: Welcome Talks, Sam Flynn and Russell Thomas, United Kingdom
09.15 - 10:00: State of Minibeam Radiotherapy, Yolanda Prezado, France
10:00 - 10:15: Challenges combining proton minibeams with target motion, Oxana Actis, Switzerland
10:15 - 10.30: Generation of micrometer electron beam from FLASHlab@PITZ, Xiangkun Li, Germany
10:45 - 11:00: MiniBee Project: Proton minibeam beamline for preclinical experiments in small animals, Aikaterini Rousseti, Germany
11:00 - 11:15: Coffee Break
11:15 - 11:35: Exploring Technical and Clinical Aspects of Lattice Radiotherapy, Maxwell Robinson/Adam Aitkenhead, United Kingdom
11:35 - 11:50: A Preclinical Setup to Inform the Clinical Introduction of Lattice Radiotherapy, Kristoffer Petersson, United Kingdom
11.50 - 12:05: Design and Characterization of Electron Minibeams from a Modified Clinical Accelerator, Umberto Deut, Italy
12:00 - 12:30: How can BeO optically stimulated luminescence dosimeters (OSLDs) be optimized for precise dose measurements in particle minibeam therapy (PMBT)? Gedchadapars Rattanasupha, France
12:30 - 13:30: Lunch
13:30 - 14:15: Limitations of TRS-398 and existing codes of practice, Hugo Palmans, United Kingdom
14:15 - 14:30: Exploiting the lateral fluence ripple from 3D-range modulators for proton mini-beam radiotherapy, Daria Boscolo, Italy
14:30 - 14:45: Designing a Compact Spatially Fractionated Range Shifter for Proton Radiobiology, Rebecca Habgood, United Kingdom
14:45 - 15:00: Adapting a radiopharmaceutical production medical cyclotron for high LET proton radiobiology studies at conventional and ultra-high dose rates with minibeam capabilities, Eva Kasanda, Switzerland
15:00 - 15:30: Are Radiochromic Films Suitable for Absorbed Dose in PMBT?, Mohammed Hussain, United Kingdom
15:30 - 15:45: Coffee Break
15:45 - 16:15: Clinical Perspective of PMBT, Emmanuel Jouglar, France
16:15 - 16:30: Status of the INFN MIRO (MInibeam RadiOtherapy) project and first biological investigations of the minibeam effect with electron beams, Francesco Romano, Italy
16:30 - 16:45: Enhanced peak-to-valley dose ratio for mega-voltage photon mini-beam radiotherapy using magnetically confined electrons, Annalisa Walpen, Switzerland
16:45 - 17:00: Interlacing Proton, Helium, and Carbon Ion Minibeams in Longitudinally Heterogeneous Treatment Plan Simulations, Thandar Aung, Germany
17:00 - 17:15: Design and Characterization of Electron Minibeams from a Modified Clinical Accelerator, Umberto Deut, Italy
19:00: Meal reservation at The King's Head, Teddington
Wednesday 19 March 2025, Day 2 of the Workshop:
09:00 - 09:30: Unanswered Questions in Radiobiology, Jason Parsons, United Kingdom
09:30 - 09:45: Experimental Evidence and Quantification of pMBRT’s Efficacy in Normal Tissue Sparing in a Murine Model, Fardous Reaz, Denmark
09:45 - 10:00: Proteomic Investigation of Rat Orthotopic Glioblastoma and Healthy Brain Responses to Proton Minibeam Radiation Therapy, Loris Roncali, Spain
10:00 - 10:15: Neon Minibeam Radiotherapy: Tissue Preservation in Abdominal Irradiation, Angela Corvino, France
10:30 - 11:00: Exploring the Role of Tissue Organization in Proton Minibeam Radiotherapy, Judith Reindl, Germany
11:00 - 11:15: Coffee Break
11:15 - 11:30: Study of the biomolecular response to neon minibeam radiation therapy in healthy and tumour cell lines through synchrotron-based infrared microspectroscopy, Roberto González Vegas, Spain
11:30 - 11:45: Use of a CMOS detector in the commissioning of a proton/helium ion microbeam facility, Tony Price, United Kingdom
12:00 - 12:15: Advancing pMBRT for Clinical Use: Experimental Validation of Proton Minibeam Dose Calculations Using a Commercial TPS Platform, Jessica Neubauer, Germany
12:30 - 13:30: Lunch
13:30 - 14:00: Clinical implementation of novel particle therapies: Proton Pencil Beam Scanning and Ultra-high dose rate proton FLASH, Richard Amos, United Kingdom
14:00 - 15:30: Roadmap for Clinical Transition Breakout Groups
15:30 - 15:45: Coffee Break
15:45 - 16:45: Roadmap for Clinical Transition Discussion
16:45 - 17:00: Goodbye, and Invitation to the 4th PMBT Workshop
Note: The timing of this programme may be subject to change at short notice.
Sister Workshop: Proton Physics Research and Implementation Group (PPRIG)
NPL will also be hosting the 7th Proton Physics Research and Implementation Group (PPRIG) Workshop on the 20 and 21 of March 2025, immediately following the PMBT workshop. Established in 2012, PPRIG brings together researchers and industry professionals to collaborate on proton therapy research and its clinical applications. The two-day PPRIG event includes:
Invited speakers
Conference talks
Poster sessions
Discussions on emerging proton therapy techniques and innovations
Participants of the PMBT workshop are welcome to extend their stay and join the PPRIG workshop for a deeper dive into proton therapy research and standards. More up to date information will be available at http://www.pprig.co.uk/pprig/meetings/.
